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  • Writer's pictureWendong Chen

Cognitive impairment makes substantial contribution to the disease burden of multiple sclerosis.


The collaborative project between Nomine Health and Peking Union Medical College Hospital titled 'The Impact of Cognitive Impairment on Disease Burden in Chinese Multiple Sclerosis Patients: A Model Simulation Study' recently published its research findings in the journal of Multiple Sclerosis and Related Disorders, an internationally renowned journal in the field of multiple sclerosis with an impact factor of 4.808 in 2021. This study utilized a decision analysis model to simulate the lifelong cumulative risk of cognitive impairment, life expectancy, quality-adjusted life years, lifelong direct medical costs, and indirect costs in newly diagnosed Chinese patients with relapsing-remitting multiple sclerosis, reflecting the impact of multiple sclerosis on disease burden. The research results showed that the majority of multiple sclerosis patients are likely to experience cognitive impairment during their lifetime, and the occurrence of cognitive impairment substantially increases the disease burden in patients with relapsing-remitting multiple sclerosis. These findings suggest that future clinical treatment management and health policy formulation for multiple sclerosis patients should take into consideration the impact of cognitive impairment in this disease. For more information about this study, please click here.

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