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Clinical Burden of Post-Ablation Atrial Fibrillation Recurrence in East Asia
Recently, the collaborative research project between Normin Health and Xiangya Hospital of Central South University, titled "Clinical Burden of Post-ablation Atrial Fibrillation Recurrence in East Asia: A Systematic Literature Review," was successfully published in the SCI journal Arrhythmia & Electrophysiology Review. Adhering to PRISMA guidelines, the study conducted a comprehensive systematic review and meta-analysis to evaluate clinical characteristics, recurrence pattern

Wendong Chen
Jul 192 min read


Real-World Reliability and Validity of EQ-5D in Chinese Patients with Cardiovascular Diseases
Recently, the collaborative research project between Normin Health and the Department of Cardiology at Xiangya Hospital, Central South University (led by Prof. Ruizheng Shi), titled "Real-World Reliability and Validity of EQ-5D in Chinese Patients With Cardiovascular Diseases: A Cross-Sectional Study," was successfully published in the ISPOR journal Value in Health Regional Issues. The study systematically evaluated the psychometric performance of the EuroQol 5-dimension 5-le

Wendong Chen
Apr 12 min read


Health Utility Gains by PASI Response Status in Chinese Patients with Moderate-to-Severe Psoriasis
Recently, the collaborative real-world study between Normin Health, Bristol Myers Squibb (BMS), Xiangya Hospital of Central South University, and Beijing Jishuitan Hospital, titled "Health utility by Psoriasis Area and Severity Index response status after biologic induction therapy in Chinese patients with moderate to severe psoriasis," was successfully published in the Journal of Comparative Effectiveness Research. The study investigated the empirical relationship between cl

Wendong Chen
Mar 222 min read


Real-World Performance of EQ-5D-5L in Chinese Patients with Hematologic Malignancies
Recently, the collaborative study between Normin Health and the hematology team at Xiangya Hospital, Central South University (led by Prof. Yajing Xu), titled "Reliability and validity of EuroQol-5 Dimensions-5 Levels in patients with haematologic malignancies: a cross-sectional study in China," was successfully published in the SCI journal BMJ Open. The study evaluated the reliability, validity, and concordance of the EQ-5D-5L instrument against health preferences elicited v

Wendong Chen
Mar 191 min read


Real-World Clinical Outcomes of Autologous Stem Cell Transplantation in Multiple Myeloma
Recently, the comprehensive real-world evidence synthesis conducted by Normin Health, titled "Real-world clinical outcomes of autologous stem cell transplantation in Chinese patients with newly diagnosed multiple myeloma: a systematic literature review," was successfully published in the SCI journal Therapeutic Advances in Hematology. The study systematically reviewed and synthesized clinical evidence to evaluate therapeutic response, long-term survival, stem cell mobilizatio

Wendong Chen
Feb 92 min read


Cost-Effectiveness of Recombinant Factor VIII Prophylaxis in Severe Hemophilia A in China
Recently, the collaborative pharmacoeconomic study involving Normin Health and academic health economists, titled "Impact of Inhibitor Development on the Cost Effectiveness of Prophylactic Treatment with Recombinant Factor VIII in Previously Untreated Patients with Severe Hemophilia A," was successfully published in the SCI journal PharmacoEconomics - Open. From the perspective of the Chinese healthcare system, the study developed a lifetime decision-analytic model to compare

Wendong Chen
Dec 3, 20251 min read


Mapping DLQI to EQ-5D Health Utility in Chinese Patients with Moderate-to-Severe Psoriasis
Recently, the collaborative methodology study between Normin Health, Xiangya Hospital of Central South University, and Bristol Myers Squibb (BMS), titled "Mapping Dermatology Life Quality Index with EQ-5D health utility index score in Chinese patients with moderate to severe psoriasis," was successfully published in the Journal of Comparative Effectiveness Research. The study developed and validated statistical mapping algorithms to estimate EuroQol 5-dimension (EQ-5D) health

Wendong Chen
Jul 18, 20251 min read


Dr. Wendong Chen Delivers Keynote on HEOR Methodologies at the 5th Xiangya Health Management Conference
On April 19, 2025, the 5th Xiangya Health Management Academic Conference was convened in Changsha, convening leading health management scholars and healthcare executives from across China and abroad. Dr. Wendong Chen, Founder and Chief Scientist of Normin Health, was invited to deliver a keynote address titled "Health Economics and Outcomes Research (HEOR): Methods and Practice," sharing vital insights on health economic evaluation and real-world evidence generation. Key High

Wendong Chen
Apr 20, 20251 min read


Dr. Wendong Chen Appointed to the Editorial Board of Journal of Comparative Effectiveness Research
We are pleased to announce that Dr. Wendong Chen has been appointed to the Editorial Board of Journal of Comparative Effectiveness Research (JCER), effective immediately. Dr. Chen is a researcher and visiting professor specializing in health economics, real-world evidence (RWE), and health technology assessment (HTA). His work focuses on the clinical and economic value of therapies across oncology and chronic diseases, and on translating evidence into decision-ready insights

Wendong Chen
Apr 2, 20251 min read


Dr. Wendong Chen has joined the editorial board of Scientific Reports
Dr. Wendong Chen has been invited to join the editorial board of the SCI journal Scientific Reports, marking a new chapter in scientific...

Wendong Chen
Dec 8, 20241 min read


Impact of COVID-19 on Hospital Services in China
Recently, the collaborative research project between Normin Health and Xiangya Hospital of Central South University, titled "Impact of...

Wendong Chen
Dec 8, 20242 min read


Dr. Wendong Chen receives adjunct professor appointment from a top tertiary hospital in China.
On the morning of June 5, 2023, in the conference room of Xiangya Hospital, Central South University, Dr. Wendong Chen was appointed as a...

Wendong Chen
Aug 2, 20232 min read


Cognitive impairment makes substantial contribution to the disease burden of multiple sclerosis.
The collaborative project between Nomine Health and Peking Union Medical College Hospital titled 'The Impact of Cognitive Impairment on...

Wendong Chen
Aug 2, 20231 min read


Is personalized IL-17A inhibitor treatment needed for patients with severe psoriasis?
Nomine Health collaborates with Xiangya Hospital of Central South University to publish an article titled 'Do Severe Plaque Psoriasis...

Wendong Chen
Aug 2, 20231 min read


TKI treatment failure is driving up the disease burden of CML
Normin Health just published a study leveraging the existing literature evidence addressing the disease burden of Chinese patients with...

Wendong Chen
May 25, 20221 min read


Reducing uncertainty of economic evaluation using real-world data.
It is even more challenging to navigate in the mess of real-world data for the economic values of medical devices. We believe that our...

Wendong Chen
Feb 16, 20221 min read


Case study for medical devices assessment in real-world setting
Normin Health just published a retrospective cohort study assessing powered stapler in video-assisted thoracic surgery (VATS) lobectomy...

Wendong Chen
Jul 26, 20211 min read


Clinical and Economic Impact of Oxidized Regenerated Cellulose for Surgeries in a Chinese Tertiary Hospital
Recently, the collaborative real-world study between Xiangya Hospital of Central South University and Normin Health, titled "Clinical and economic impact of oxidized regenerated cellulose for surgeries in a Chinese tertiary care hospital," was successfully published in the Journal of Comparative Effectiveness Research. The study evaluated the clinical and economic impact of oxidized regenerated cellulose (ORC) compared to conventional non-ORC hemostatic techniques across ten

Wendong Chen
Sep 21, 20201 min read


Reimbursing infliximab for Crohn's disease is cost-effective in Chinese patients.
One of the collaboration projects of Normin Health has been published in Advances in Therapy. This project leveraged the real-world data...

Wendong Chen
Dec 16, 20191 min read


Dr. Wendong Chen receives specially-appointed professor from Central South University in China
Dr. Wendong Chen has received the specially appointed professor from the Second Xiangya Hospital of Central South University in Changsha,...

Wendong Chen
Dec 16, 20191 min read
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